follow these steps:
1. Hematopoietic Stem Cells (HSCs)Start with: Hematopoietic Stem Cells (HSCs)HSCs are multipotent cells in the bone marrow that can differentiate into various blood cell types.
2. Differentiation into Lineages HSCs split into two main lineages:
1. Myeloid Lineage
2. Lymphoid Lineage
👉Myeloid Lineage
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Common Myeloid Progenitor (CMP)Differentiates into:
Erythrocytes (Red Blood Cells)
Megakaryocytes (produce Platelets)
Granulocyte-Macrophage Progenitor (GMP)GMP differentiates into:
▪️Neutrophils
▪️Eosinophils
▪️Basophils
▪️Monocytes (which can further become Macrophages or Dendritic Cells
4. Lymphoid Lineage Common Lymphoid Progenitor (CLP)Differentiates into:
B Lymphocytes (B Cells)
T Lymphocytes (T Cells)
Natural Killer (NK) Cells
Dendritic Cells (some types)